Re: CS's Absorbtion w re to Intestinal Flora
(It would seem to me that, perhaps, a persons overall response to oral CS (along with also considering it's oxidative rating as a "1.0") and for this discussion how oral CS would or would not affect GI Tract organisms, is based on the buffering makeup of fluid ingested and our personel system's fluid movement health).
(Not regarding alcohols and many meds, I dont see distilled water CS leaking in considered amounts(unless extreme body dehydration is active)past stomach tissue bypassing intestinal organisms, because of its basic functioning.)( While Mercola's site is valuable for its large alternative data base, it's not always 100%reliable.)
•(Oral ingestion of) Water diffuses (thru membrane tissue) in response to the osmotic gradient established by sodium - into intercellular spaces.
The transiting of water, like many aspects of gut permeability, varies along the length of the gut. The proximal small intestine functions as a permeable mixing segment, and absorption of water is basically isotonic. That is, water is not absorbed until the ingesta has been diluted out to just above the osmolarity of blood. The ileum and especially the colon are able to (discharge) water against an osmotic gradient of several hundred milliosmols.
The process that takes place is establishment of an electrochemical gradient of sodium across the epithelial cell boundary. This is a critical concept and actually quite interesting. Also understanding this process has undeniably resulted in the saving of millions of lives(by the use of added salt in critical care I.V.solution administering)
Thus the flow and accumulation of sodium is ultimately responsible for (the movement) of water, amino acids and carbohydrates.
There is still considerable uncertainty about how water is absorbed(-----), but Curran and Macintosh present an explanation known as the "three compartment - two membrane model" that accounts for many aspects of water transport in the gut and other tissues.
It is proposed that the epithelium consists of three compartments separated by two membranes which differ in permeability.
In this situation, water will move against an osmotic gradient from compartment A to compartment C as long as two conditions are met:
•The osmolarity in compartment B is greater than in compartment A.
•The permeability of membrane 1 is less than that of membrane 2.
In such a case, the higher osmolarity in compartment B relative to A or C provides the driving force for movement of water from A to B. As water flows into compartment B, the hydrostatic pressure in that compartment increases, forcing water to flow through membrane 2 and into the lowest osmolarity compartment C.